medium · LSAT Reading Comprehension

Generating a new neuron is only the beginning. For such a cell to become functionally integrated into the brain, it must do more than survive and migrate to its destination; it must wire itself into the surrounding tissue by forming synaptic connections with the neural circuits already in place. Only once these connections are established does the new neuron contribute to the brain's activity.

According to the passage, which one of the following is necessary for a newly generated neuron to become functionally integrated?

  1. It establishes synaptic links with the neural circuitry already present in the surrounding tissue
  2. It is activated by pharmacological agents introduced from outside the body
  3. It travels to the prefrontal cortex immediately after it is generated
  4. It replaces every neuron that has been lost to a traumatic brain injury
  5. It divides repeatedly to produce a colony of identical neurons before wiring in

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