easy · LSAT Reading Comprehension

The cell membrane, also known as the plasma membrane, is a semi-permeable lipid bilayer that surrounds every living cell. Its primary function is to regulate the passage of molecules into and out of the cell, maintaining a stable internal environment known as homeostasis. The membrane is composed mainly of phospholipids, which have hydrophilic heads and hydrophobic tails. This arrangement creates a barrier that prevents most water-soluble substances from crossing freely. Integral proteins embedded within the bilayer serve as channels or transporters for specific ions and molecules. For instance, the sodium-potassium pump is a protein that actively moves ions against their concentration gradients to maintain the cell's electrical potential. In addition to transport, the membrane plays a vital role in cell signaling. Carbohydrate chains attached to proteins or lipids on the exterior surface act as identification markers, allowing the immune system to distinguish between self and non-self cells. Without these markers, the body would be unable to coordinate a defense against invading pathogens. Furthermore, cholesterol molecules interspersed within the bilayer help to maintain membrane fluidity, ensuring that the membrane remains flexible but stable across a range of temperatures. As researchers develop new targeted drug delivery systems, understanding the intricate structure of the plasma membrane is critical for ensuring that therapeutic agents can bypass these cellular defenses effectively.

Which of the following best describes the function of the reference to the sodium-potassium pump?

  1. It rebuts the earlier statement that phospholipids form the bulk of the membrane.
  2. It shows that carbohydrate identification markers are dispensable for homeostasis.
  3. It offers a concrete instance of an integral protein carrying out active transport across the membrane.
  4. It establishes that every ion must move against its concentration gradient to enter a cell.
  5. It demonstrates how the membrane lets water-soluble substances diffuse freely once a channel protein is present.

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