medium · LSAT Reading Comprehension

For decades neuroscientists assumed the adult brain was structurally static. That assumption was overturned by the discovery that certain regions, notably the hippocampus, continue to generate new neurons throughout adulthood. This finding has raised hopes that such regeneration might one day be harnessed to treat conditions like stroke and Alzheimer's disease. Yet substantial obstacles remain: newly formed neurons must survive, migrate, and integrate into existing circuits before any human therapy becomes feasible, and the human rate of neuron production appears far lower than that observed in rodents.

Which one of the following most accurately expresses the main point of the passage?

  1. The discovery that the adult brain can form new neurons is a major advance with real therapeutic promise, though formidable hurdles stand between it and clinical treatments.
  2. The longstanding belief in a static adult brain was correct for every brain region apart from the hippocampus.
  3. Researchers should redirect funding away from Alzheimer's drug development and toward programs that promote new-neuron formation.
  4. The human brain produces more new neurons than the brains of any other mammalian species.
  5. Adult neurogenesis has already been translated into effective therapies for stroke and Alzheimer's disease.

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