hard · NCLEX-RN Pharmacological and Parenteral Therapies
A clinic nurse is performing a pre-infusion assessment on a 61-year-old client with ulcerative colitis who is scheduled to receive an initial dose of infliximab. Which of the following findings from the laboratory results require the nurse to hold the infusion and notify the healthcare provider? Select all that apply.
- Positive interferon-gamma release assay (IGRA) test for tuberculosis.
- If a live vaccine is essential, coordinate with the prescriber; a common rheumatology approach is to hold adalimumab for one dosing interval before the vaccine and for 4 weeks afterward.
- Hemoglobin of 11.2 g/dL [reference range: 12.0-16.0 g/dL].
- Positive hepatitis B surface antigen (HBsAg) with positive HBV DNA.
- Serum creatinine of 1.9 mg/dL [reference range: 0.6-1.2 mg/dL].
- Absolute Neutrophil Count (ANC) of 850/mm3 [reference range: 1,500-8,000/mm3].
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