medium · NCLEX-RN Pharmacological and Parenteral Therapies

A client is receiving high-dose cyclophosphamide for a hematologic malignancy.

Which nursing intervention is most critical to prevent the complication of hemorrhagic cystitis?

  1. Encourage aggressive oral or IV hydration and frequent voiding.
  2. Apply a cold compress to the lower abdomen if suprapubic pain occurs.
  3. Administer an antiemetic 30 minutes prior to the start of the infusion.
  4. Monitor the client's temperature every 4 hours for signs of infection.

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