hard · NCLEX-RN pharmacology
A nurse is preparing to administer doxorubicin to a 48-year-old client with lymphoma who has received a cumulative lifetime dose of 400 mg/m². Which clinical findings or diagnostic results require the nurse to hold the medication and notify the healthcare provider? Select all that apply.
- A new echocardiogram report indicating a left ventricular ejection fraction (LVEF) of 44%.
- New-onset grade 2 peripheral neuropathy in the bilateral lower extremities.
- Development of a new S3 gallop, jugular venous distention, and fine bilateral basilar crackles.
- A decline in the left ventricular ejection fraction (LVEF) of 15% from the pre-treatment baseline of 62%.
- Mild alopecia with 50% hair thinning reported since the second chemotherapy cycle.
- A current serum potassium level of 4.1 mEq/L (reference range: 3.5-5.0 mEq/L).
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