hard · NCLEX-RN Safety and Infection Prevention and Control

A surveillance stool PCR for an asymptomatic 82-year-old female client in the intensive care unit is positive for carbapenem-resistant Enterobacterales (CRE) colonization. The client is alert and oriented, passing soft, formed stool once daily, with a temperature of 98.6 F (37.0 C), blood pressure 118/72 mm Hg, and heart rate 68/min. The provider orders empiric intravenous imipenem/cilastatin and blood, urine, and sputum cultures. Which actions by the nurse demonstrate safe clinical judgment and diagnostic stewardship? Select all that apply.

  1. Implement contact precautions immediately and post appropriate signage.
  2. Draw the ordered blood cultures and collect urine and sputum specimens immediately.
  3. Administer the imipenem/cilastatin after cultures are drawn to ensure early sepsis treatment.
  4. Question the order for empiric imipenem/cilastatin.
  5. Clarify with the provider whether the cultures are indicated given the lack of clinical infection cues.

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