medium · NCLEX-RN Safety and Infection Prevention and Control

A client is being treated for a deep vein thrombosis with a continuous heparin infusion. The current aPTT is 110 seconds (Reference: 30-40 seconds; Therapeutic: 1.5-2.5 times reference).

Which action should the RN take first?

  1. Administer protamine sulfate IV push as an antidote.
  2. Stop the infusion and assess the client for signs of bleeding.
  3. Draw a repeat aPTT from the opposite arm to verify the result.
  4. Decrease the infusion rate by 200 units/hour per the protocol.

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