medium · GMAT Verbal

Senescent cells accumulate with age and secrete inflammatory molecules. Researchers argue that this accumulation actively drives age-related decline, not merely accompanies it, citing that senolytic drugs, which selectively clear senescent cells from aged mice, improved the mice's physical function.

Which of the following, if true, most strengthens the researchers' argument?

  1. Senescent cells are also found, in smaller numbers, in young animals.
  2. The senolytic drugs had no effect on physical function in mice that had few senescent cells to begin with.
  3. Senolytic drugs are currently expensive to produce at scale.
  4. Some senescent cells help wounds heal by signaling nearby tissue.
  5. Aged mice tend to be less physically active than young mice overall.

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