hard · GMAT Verbal

Senescent cells accumulate with age and secrete inflammatory molecules. Researchers argue that this accumulation actively drives age-related decline, not merely accompanies it, citing that senolytic drugs, which selectively clear senescent cells from aged mice, improved the mice's physical function.

Which of the following, if true, most strengthens the researchers' argument?

  1. Senescent cells are also found, in considerably smaller numbers, within the tissues of healthy young animals.
  2. The senolytic drugs had no effect on physical function in mice that had few senescent cells to begin with.
  3. The senolytic drugs are currently quite expensive and difficult to produce at large commercial scale.
  4. Some senescent cells actively help wounds heal by sending growth signals to the surrounding tissue.
  5. Aged mice generally tend to be markedly less physically active than young mice across nearly all measured tasks overall.

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