medium · MCAT bio-biochem

During the repolarization phase of an action potential in a neuron, which of the following events is primarily responsible for returning the membrane potential toward its resting value?

  1. Closing of voltage-gated potassium channels.
  2. Activation of the Na^+/K^+ pump to restore ion gradients.
  3. Opening of voltage-gated potassium channels and inactivation of sodium channels.
  4. Opening of voltage-gated sodium channels.

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