medium · MCAT bio-biochem
A patient is admitted to the emergency department with a severe systemic infection and a core fever of 40.5^circC. Laboratory results indicate a normal blood pH.
How does this patient's O_2 saturation at a tissue P_O_2 of 40 mmHg compare to a healthy individual at 37^circC?
- The saturation will be lower due to a right-shift caused by the fever.
- The saturation will be higher because the kinetic energy of O_2 molecules increases binding frequency.
- The curve shifts to the left to protect the brain from oxygen deprivation during hyperthermia.
- The saturation remains unchanged if the pH is normal, as acidity is the primary driver of the Bohr effect.
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