medium · MCAT bio-biochem

An experimental drug blocks the inactivation gate of voltage-gated Na⁺ channels in neurons.

If a stimulus reaches the threshold, how would the shape of the resulting action potential be altered?

  1. The threshold potential would shift toward a more positive membrane value.
  2. The repolarization phase would be significantly delayed or absent.
  3. The hyperpolarization phase would occur more rapidly than it normally does.
  4. The depolarization phase would simply fail to occur at all.

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