medium · MCAT bio-biochem

While studying the enzyme Phosphofructokinase-1 (PFK-1), a student observes that adding ATP to the reaction mixture decreases the rate of glycolysis. However, adding AMP increases the rate.

What type of regulation is being demonstrated?

  1. Zymogen activation
  2. Irreversible covalent modification
  3. Competitive inhibition by ATP
  4. Allosteric regulation

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