medium · MCAT bio-biochem
In prolonged fasting or untreated diabetes, the body produces ketone bodies.
Which of the following best describes the biochemical source of ketones and their clinical impact on blood chemistry?
- Ketones are produced from excess Acetyl-CoA during high beta-oxidation; their accumulation leads to metabolic acidosis.
- Ketones are produced from the breakdown of proteins in the muscle; their accumulation leads to high blood urea nitrogen (BUN).
- Ketones are produced from the incomplete oxidation of glucose in the brain; their accumulation leads to respiratory alkalosis.
- Ketones are synthesized from lactate via the glyoxylate cycle; their accumulation leads to hypoglycemia.
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