hard · MCAT bio-biochem
A metabolic study evaluates an enzyme that exhibits a decrease in both V_max and K_M upon the addition of an inhibitor.
Which of the following best describes the mechanism and binding site of this inhibitor?
- Uncompetitive inhibition; binds only to the enzyme-substrate complex.
- Competitive inhibition; binds only to the free enzyme at the active site.
- Mixed inhibition; binds with higher affinity to the free enzyme than to the enzyme-substrate complex.
- Noncompetitive inhibition; binds with equal affinity to the free enzyme and the enzyme-substrate complex.
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