medium · MCAT bio-biochem

A hiker is severely dehydrated. Their body releases Antidiuretic Hormone (ADH) and Aldosterone to restore homeostasis.

Which of the following correctly distinguishes the mechanisms of these two hormones in the nephron?

  1. ADH increases Na^+ excretion; Aldosterone instead promotes water reabsorption in the proximal convoluted tubule segment.
  2. ADH increases water permeability in the collecting duct; Aldosterone promotes Na^+ reabsorption in the distal tubule.
  3. Both hormones act solely by increasing the glomerular filtration rate (GFR) at the afferent arteriole.
  4. ADH causes vasodilation of the afferent arteriole; Aldosterone decreases the osmolarity of the renal medulla over time.

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