medium · MCAT bio-biochem
Aldosterone is a steroid hormone that acts on the distal convoluted tubule and collecting duct.
Which of the following describes its primary molecular action and its ultimate effect on blood pressure?
- Promotes renal excretion of Na+ in exchange for Ca^2+ to regulate osmolarity.
- Inhibits the renin-angiotensin system via negative feedback, thereby decreasing overall blood pressure.
- Binds to cell-surface receptors to increase intracellular cAMP, leading directly to renal water reabsorption.
- Binds to cytoplasmic receptors to upregulate Na^+/K^+ pumps, increasing blood pressure.
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