medium · MCAT bio-biochem
During a period of heavy exercise, Phosphofructokinase-1 (PFK-1) activity increases in muscle cells.
Which of the following metabolic signals most likely accounts for this activation, and what is the downstream fate of the resulting pyruvate if oxygen delivery is insufficient?
- High Citrate levels; oxidation in the Citric Acid Cycle.
- High AMP levels; reduction to lactate in the cytoplasm.
- High Glucagon levels; conversion to Glucose via gluconeogenesis.
- High ATP levels; conversion to Acetyl-CoA in the mitochondria.
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