medium · MCAT chem-phys

A lab technician uses thin-layer chromatography (TLC) to separate two compounds. Compound A is polar, and Compound B is nonpolar.

Using a silica gel plate (polar stationary phase) and a nonpolar solvent (mobile phase), which compound will travel further?

  1. Compound A, because polar compounds move fastest in nonpolar solvent.
  2. Compound B, because it interacts less with the stationary phase.
  3. Both move the same distance via capillary action alone.
  4. Neither compound will move at all, given that the solvent used is nonpolar.

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