medium · MCAT chem-phys
A student compares the S_N1 and S_N2 mechanisms in organic chemistry.
Which of the following conditions most favors the S_N2 pathway for a substitution reaction?
- A primary substrate in a polar aprotic solvent with a strong nucleophile.
- A tertiary substrate in a polar protic solvent with a weak nucleophile.
- A primary substrate in a polar protic solvent with a sterically hindered base.
- A secondary substrate at high temperatures in a nonpolar solvent.
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