medium · MCAT chem-phys

A researcher is studying the Bohr effect in human hemoglobin.

Which of the following conditions would cause the oxygen-hemoglobin dissociation curve to shift to the right, favoring the unloading of oxygen in tissues?

  1. Increased concentration of CO₂ and decreased pH.
  2. Increased partial pressure of oxygen (P_O_2).
  3. Presence of Carbon Monoxide (CO).
  4. Decreased temperature and increased pH.

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