medium · MCAT chem-phys

Why are termolecular (three-body) elementary steps extremely rare in reaction mechanisms?

  1. Termolecular steps would violate the fundamental law of conservation of mass here.
  2. Termolecular collisions occur only within rigid solid-phase lattices, never gas or solution mechanisms.
  3. The activation energy needed for any three-molecule encounter is always too high to overcome.
  4. The probability of three molecules colliding simultaneously with correct orientation is very low.

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