hard · MCAT
A graduate student experiencing chronic stress over a six-month period enters a phase characterized by the depletion of physiological resources and a significantly weakened immune system.
According to Selye's General Adaptation Syndrome, what stage is this student in, and what is the primary neuroendocrine driver of the subsequent hippocampal atrophy and memory deficits?
- Exhaustion stage; over-activation of the parasympathetic rebound
- Exhaustion stage; prolonged exposure to high cortisol levels
- Resistance stage; increased catecholamine release from the adrenal medulla
- Alarm stage; activation of the hypothalamic-pituitary-adrenal (HPA) axis
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