hard · MCAT

A clinician uses a chemical cold pack to treat a patient's sprained ankle. The pack works by dissolving ammonium nitrate in water, a process that is endothermic (ΔH > 0).

If the cold pack works spontaneously, what must be true about the entropy change (ΔS) of the system?

  1. ΔS must be zero, as the process is driven solely by heat transfer.
  2. ΔS must be positive, such that TΔS > ΔH.
  3. ΔS does not affect spontaneity in processes involving phase changes.
  4. ΔS must be negative to compensate for the positive enthalpy.

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