medium · NCLEX-RN psychosocial
A client receiving 10 mg of haloperidol daily develops a temperature of 39.4circ C (102.9circ F), profound 'lead-pipe' muscle rigidity, and fluctuating consciousness.
Which pathophysiologic mechanism is most likely responsible for these findings?
- Dopamine receptor blockade in the basal ganglia and hypothalamus
- Acute hypersensitivity reaction causing systemic vasodilation
- Excessive accumulation of serotonin in the synaptic clefts
- Anticholinergic crisis causing reduced sweat production
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