medium · NCLEX-RN safety

The RN is caring for a client with a documented anaphylactic allergy to penicillin. The provider orders cefazolin 1 g IV every 8 hours for a surgical site infection.

Which action by the RN is most appropriate?

  1. Administer the dose as ordered because it is not a penicillin-class drug.
  2. Ensure diphenhydramine is available at the bedside and give the dose.
  3. Administer the cefazolin over 60 minutes instead of 30 minutes.
  4. Hold the medication and contact the provider to discuss cross-sensitivity.

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