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Extravasation

NCLEX-RN glossary · Pharmacological And Parenteral Therapies

Definition

The unintended leakage of vesicant medications from the intravenous compartment into the surrounding interstitial tissue.

Extravasation in plain English

Unlike simple infiltration, extravasation of vesicants causes severe tissue necrosis and potential permanent loss of limb function. The tempting mistake is failure to stop the infusion immediately at the first sign of site discomfort, redness, or a change in the client's sensation.

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