Loop and potassium-sparing diuretics
NCLEX-RN glossary · Pharmacological And Parenteral Therapies
Definition
Two medication classes that increase urine output; loop diuretics (furosemide) deplete potassium, whereas potassium-sparing agents (spironolactone) retain it.
Loop and potassium-sparing diuretics in plain English
Potassium imbalances from these drugs can cause fatal cardiac arrhythmias; levels must be monitored before administration. The tempting mistake is administering a loop diuretic to a client with pre-existing hypokalemia without obtaining a replacement order.
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