Tumor lysis syndrome
NCLEX-RN glossary · Pharmacological And Parenteral Therapies
Definition
An oncology emergency caused by the rapid breakdown of cancer cells, releasing intracellular contents into the bloodstream.
Tumor lysis syndrome in plain English
It is characterized by high potassium, high uric acid, high phosphate, and low calcium; can lead to acute renal failure and cardiac arrest. The tempting mistake is failure to prioritize aggressive hydration as the primary preventative measure before starting chemotherapy.
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