hard · MCAT bio-biochem

During a state of severe dehydration, which of the following describes the synergistic action of ADH and aldosterone on the nephron?

  1. Aldosterone increases the osmotic drive for water reabsorption, while ADH provides the pathway for that water to move.
  2. ADH lowers blood pressure to cut glomerular filtration, while aldosterone raises excretion of excess salts.
  3. Aldosterone acts on the proximal tubule to reclaim glucose, while ADH acts on the loop of Henle to secrete urea.
  4. Both hormones act directly on the glomerular capillaries to lower net filtration pressure and thereby conserve circulating blood volume.

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