medium · MCAT bio-biochem

How does an increase in blood P_CO2 and a subsequent decrease in blood pH (the Bohr effect) affect the oxygen-hemoglobin dissociation curve?

  1. The curve shifts to the left, increasing oxygen affinity to help load oxygen in the lungs.
  2. The curve becomes linear, indicating that hemoglobin has lost its cooperative binding property.
  3. The curve shifts upward, indicating that hemoglobin can carry more total oxygen.
  4. The curve shifts to the right, decreasing oxygen affinity to promote oxygen unloading in tissues.

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