medium · MCAT bio-biochem

How does the presence of cholesterol affect the fluidity of a biological membrane at high and low temperatures?

  1. Cholesterol decreases membrane fluidity at all temperatures by increasing the overall thickness of the lipid bilayer.
  2. Cholesterol increases fluidity at all temperatures because it disrupts the tight packing of the fatty acid tails.
  3. Cholesterol acts as a 'fluidity buffer,' decreasing fluidity at high temperatures and increasing it at low temperatures.
  4. Cholesterol has no real effect on fluidity, since its only physiological role is in intracellular signaling cascades.

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