medium · MCAT bio-biochem
A patient with severe metabolic alkalosis (blood pH 7.6) is monitored for oxygen saturation.
What is the expected position of their oxygen-hemoglobin dissociation curve relative to the standard?
- The P_50 will be 35 mmHg, representing a significant decrease in affinity.
- The curve becomes hyperbolic, losing its sigmoidal shape due to the lack of available protons.
- It is shifted to the right, ensuring tissues receive extra oxygen during the alkalotic state.
- It is shifted to the left, which can lead to tissue hypoxia despite high arterial oxygen saturation.
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