medium · MCAT bio-biochem

In the proximal convoluted tubule (PCT), approximately 65% of the filtered water is reabsorbed.

What is the osmolarity of the filtrate at the end of the PCT compared to the initial filtrate in Bowman's space?

  1. It is significantly lower because solutes are actively transported out while the tubule remains impermeable to water.
  2. It depends entirely on the levels of circulating antidiuretic hormone (ADH).
  3. It is significantly higher because only water is reabsorbed in this segment.
  4. It is essentially the same (iso-osmotic) because solutes and water are reabsorbed proportionately.

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