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The development of 'synthetic lethality' in cancer research involves identifying pairs of genes where the loss of either gene alone is non-essential for cell survival, but the loss of both genes leads to cell death. By targeting a gene that is a synthetic lethal partner to a mutation already present in a tumor, researchers can ______ destroy cancer cells while sparing healthy tissue that lacks the mutation.

  1. Thoroughly
  2. Eventually
  3. Selectively
  4. Arbitrarily

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