medium · LSAT Logical Reasoning

In a study of 1,000 office workers, those who reported drinking at least four cups of coffee a day had a 25 percent lower risk of developing Type 2 diabetes than those who drank none. Therefore, drinking coffee prevents diabetes.

Which one of the following, if true, most seriously challenges the conclusion?

  1. Heavy coffee drinkers in the study were also far more likely to exercise regularly, and regular exercise is itself known to lower diabetes risk.
  2. A smaller, lower-powered study of just 100 office workers detected no statistically significant relationship between coffee intake and diabetes.
  3. Some of the workers who reported drinking four full cups of coffee a day nonetheless still went on to develop Type 2 diabetes during the study.
  4. The caffeine in coffee is known to produce an elevated resting heart rate, jitteriness, and chronic insomnia in certain sensitive individuals.
  5. Regular coffee consumption has also been separately linked to a reduced risk of several other serious conditions besides Type 2 diabetes alone.

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